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Hawking\'s black hole information paradox is one of the great thought experiments in physics. It points to a breakdown of some central principle of physics, though which one breaks down is still in dispute. It has led to the discovery of ideas that seem to be key to unifying quantum mechanics and gravity, namely the holographic principle and gauge/gravity duality. I review this subject, and discuss ongoing work and future directions.

Chris Isham in pre-recorded video, with Andreas Doring fielding questions and clarifications. Like watching commentators Scott Hamilton and Katarina Witt analyze Kristi Yamaguchi\'s performance at the World Figure Skating Championships for CBS News, join us for something different in quantum foundations. Chris Isham parries the intricacies of topos theory; Andreas Doring shows us how to see the moves in slow motion. Bring your own popcorn and plenty of questions.

I will summarize current observational constraints in cosmology with emphasis on what we have learned about the properties of the primordial density perturbations. I will describe future directions including observations of high redshift neutral hydrogen through is 21 cm line.