Scattering Kernel for Aperture Modulated Total Body Irradiation

          @misc{ scivideos_PIRSA:11070076,
            doi = {10.48660/11070076},
            url = {https://pirsa.org/11070076},
            author = {Wan, Di},
            keywords = {},
            language = {en},
            title = {Scattering Kernel for Aperture Modulated Total Body Irradiation},
            publisher = {Perimeter Institute for Theoretical Physics},
            year = {2011},
            month = {jul},
            note = {PIRSA:11070076 see, \url{https://scivideos.org/pirsa/11070076}}
          }
          

Abstract

The goal of Total Body Irradiation (TBI) is to deliver a uniform dose of radiation to the entire body, to destroy cancerous cells. Since the human body is not uniform in either density or thickness, it is difficult to deliver a uniform dose. A novel, Aperture Modulated, Total Body Irradiation (AMTBI) technique was introduced by researchers at the Tom Baker Cancer Centre to address this problem. The AMTBI technique reduces the dose deviation along the midline in the longitudinal direction to less than 5%, as compared to 15% with conventional TBI. This improvement in dose homogeneity is achieved by dynamically changing the apertures of the Multi-Leaf Collimator (MLC) according to the radiative area