Excavating the Architecture of Chromatin: From Nucleosomes to Chromosomes
APA
(2024). Excavating the Architecture of Chromatin: From Nucleosomes to Chromosomes. SciVideos. https://youtube.com/live/LXOwcM1zlgs
MLA
Excavating the Architecture of Chromatin: From Nucleosomes to Chromosomes. SciVideos, Sep. 19, 2024, https://youtube.com/live/LXOwcM1zlgs
BibTex
@misc{ scivideos_ICTS:29652, doi = {}, url = {https://youtube.com/live/LXOwcM1zlgs}, author = {}, keywords = {}, language = {en}, title = {Excavating the Architecture of Chromatin: From Nucleosomes to Chromosomes}, publisher = {}, year = {2024}, month = {sep}, note = {ICTS:29652 see, \url{https://scivideos.org/icts-tifr/29652}} }
Abstract
3D organization of eukaryotic genomes scales from nucleosomes to loops, chromatin domains and chromosome territories. Given the hierarchical nature of this organization we explored the dependence of higher order genome organization on nucleosome positioning across the genome. I will discuss the mechanism by which ATP-dependent chromatin remodeller, ISWI slides nucleosomes to position them regularly and what are the consequences of perturbing nucleosome positioning across the genome on higher order genome organization.